Decentralized Clinical Trials: How COVID Accelerated Remote Research
So much has changed as a result of the COVID-19 pandemic. Activities we once took for granted became difficult—or impossible—as the world adjusted to contain the virus. One of the most significant disruptions occurred in the way new medicines are developed. Clinical trials remain essential to advancing science and offering patients access to innovative therapies, yet lockdowns and travel restrictions reshaped how research could be conducted. As a result, organizations across the industry had to adapt quickly to keep progress moving forward.
Over the past year, the Global Life Science Alliance (GLSA) has closely observed these shifts. We believe our network partners are exceptionally well positioned to support sponsors and CROs as clinical research evolves.
Equipped for Remote Patient Monitoring
As many aspects of daily life moved into the home, clinical trial activities followed. This shift increased the need for digital platforms that allow patients to participate without traveling to outpatient centers. Solutions like Tryl help maintain patient engagement while supporting remote participation. Intuitive, user-friendly digital tools are now essential to sustaining high-quality clinical research in this new environment.
Connectivity also plays a critical role. Remote trials rely on home-use medical devices such as ECGs, blood pressure monitors, scales, and pulse oximeters—many of which operate wirelessly. Managing these interconnected devices in a reliable and cost-effective way is crucial. Kore Wireless addresses this challenge by coordinating IoT-connected devices, sourcing peripherals, and negotiating data contracts to make decentralized trials practical and scalable.
Digitized and Auditable Trial Operations
This new era of clinical research depends heavily on digital infrastructure. Moving away from paper-based systems improves accountability, efficiency, and audit readiness. Every aspect of trial oversight—from patient data capture to safety monitoring—benefits from streamlined digital processes.
The Concinnity Company provides a strong example through its digital platform for Data Monitoring and Safety Boards. Their solution enables real-time collaboration, enhances oversight, and supports safer trial conduct through efficient digital workflows.
Digitization also supports sustainability. Reducing paper trails lowers environmental impact while improving operational efficiency. DocuTrial enables clinical trial sites to operate with fully digital documentation, saving time and space while improving data security and accessibility.
Rethinking Trial Design
These operational changes require thoughtful trial design. Studies must maintain scientific integrity while accounting for the complexities of remote participation. Inference integrates biostatistics, biometrics, pharmacokinetics, and data management to help sponsors design trials that align with decentralized and hybrid models.
Maintaining High Standards
Ensuring data quality and patient safety remains critical. In long-term or chronic conditions, some patients enroll in multiple trials, which can compromise data integrity. Verified Clinical Trials addresses this issue by maintaining a comprehensive patient registry, helping sponsors and CROs avoid duplicate enrollment and protect study validity.
At GLSA, we continuously monitor trends and best practices across the clinical research landscape. We focus on identifying partners that deliver smart technology, strong service, and real value. If you would like to explore today’s clinical trial technology environment—or increase the visibility of your solution within the industry—we welcome the opportunity to connect and discuss how we can help drive meaningful impact for patients.
About GLSA
Global Life Sciences Alliance (GLSA) connects biotechs, pharma, CROs, and clinical research sites with the right experts, advisors, and solutions to accelerate development and reduce risk. With a network of more than 200 trusted partners spanning pre-clinical and clinical research, GLSA offers flexible, cost-effective access to specialized expertise and services that support early-stage biotechs, mid-size pharma, and global pharmaceutical companies.
When you need trusted, global resources to accelerate your research, GLSA helps you scale smarter and move you forward with confidence.
To learn how GLSA can support your organization, connect with Denise McNerney or Chris Matheus for a conversation about your goals and challenges.